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Index > Protein center > Cyr61(Gene name) > Rat
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  • Cyr61 (Gene name),
  • Protein CYR61 (Protein name ),  CYR61_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyr61(Ccn1;Igfbp10);
    Protein name:
    Protein CYR61;
    Alternative:
    Cysteine-rich angiogenic inducer 61;CCN family member 1;Insulin-like growth factor-binding protein 10(IBP-10;IGF-binding protein 10;IGFBP-10);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interaction with integrins is heparin- and cell-type-dependent and promotes cell adhesion.
    Function:
    Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (By similarity). CYR61-mediated gene regulation is dependent on heparin-binding (By similarity). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (By similarity). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    379
    Sequence:
    50:
    MSSSTIKTLA | VAVTLLHLTR | LALSTCPAAC | HCPLEAPKCA | PGVGLVRDGC | 
    100:
    GCCKVCAKQL | NEDCSKTQPC | DHTKGLECNF | GASSTALKGI | CRAQSEGRPC | 
    150:
    EYNSRIYQNG | ESFQPNCKHQ | CTCIDGAVGC | IPLCPQELSL | PNLGCPNPRL | 
    200:
    VKVSGQCCEE | WVCDEDSIKD | SLDDQDDLLG | FDASEVELTR | NNELIAIGKG | 
    250:
    SSLKRLPVFG | TEPRVLYNPL | HAHGQKCIVQ | TTSWSQCSKS | CGTGISTRVT | 
    300:
    NDNSECRLVK | ETRICEVRPC | GQPVYSSLKK | GKKCSKTKKS | PEPVRFTYAG | 
    350:
    CSSVKKYRPK | YCGSCVDGRC | CTPLQTRTVK | MRFRCEDGEM | FSKNVMMIQS | 
    379:
    CKCNYNCPHP | NEASFRLYSL | FNDIHKFRD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Protein CYR61
    Cat.:
    E0494r
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    96T
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    ELISA Kit for Rat Protein CYR61
    Cat.:
    E0494m
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    96T
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    ELISA Kit for Rat Protein CYR61
    Cat.:
    E0494h
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    96T
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    ELISA Kit for Rat Protein CYR61
    Cat.:
    E0494c
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    Packing:
    96T
    CLIA Kit for Rat Protein CYR61
    Cat.:
    U0494h
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    Packing:
    96T
    Range:
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    CLIA Kit for Rat Protein CYR61
    Cat.:
    U0494m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Protein CYR61
    Cat.:
    U0494c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Protein CYR61
    Cat.:
    U0494r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Protein CYR61
    Cat.:
    P0494Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Protein CYR61
    Cat.:
    P0494Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Protein CYR61
    Cat.:
    P0494Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Protein CYR61
    Monoclonal Antibody for Rat Protein CYR61
    Monoclonal Antibody for Rat Protein CYR61
    Monoclonal Antibody for Rat Protein CYR61
    Monoclonal Antibody for Rat Protein CYR61
    Protein for Rat Protein CYR61
    Protein for Rat Protein CYR61
    Protein for Rat Protein CYR61
    Protein for Rat Protein CYR61

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    References
    1. 1.
      "Muscarinic acetylcholine receptors induce the expression of the immediate early growth regulatory gene CYR61."
      Albrecht C. , von Der Kammer H. , Mayhaus M. , Klaudiny J. , Schweizer M. , Nitsch R.M.
      J. Biol. Chem.275:28929-28936(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lung.
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